Publications
The research powering the work we do.
A genetic custom-made in vivo drug screening platform for colorectal cancer patients
by Cristina de Miguel, Andrea Chai, Annick Sawala, Laura Towart and Nahuel Vilegas


A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer
by Erdem Bangi, Celina Ang, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Hope Rainey, Aye S. Moe, Chun Yee Lau, Patricia Taik, Eric Wilck, Aarti Bhardwaj, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Eric E. Schadt, Marshall R. Posner and Ross L. Cagan
A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma
by Erdem Bangi, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Sindhura Gopinath, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Huan Wang, Jorge omez, John Mascarenhas, Aye S. Moe, Chun Yee Lau, Patricia Taik, Chetanya Pandya, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Celina Ang, Eric E. Schadt, Marshall R. Posner and Ross L. Cagan


Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function
by Santiago Nahuel Villegas, Dolors Ferres-Marco, María Domínguez
One hundred years of Drosophila cancer research: no longer in solitude
by Santiago Nahuel Villegas


Functional exploration of colorectal cancer genomes using Drosophila
by Erdem Bangi, Claudio Murgia, Alexander G.S. Teague, Owen J. Sansom and Ross L. Cagan
Transformed Drosophila Cells Evade Diet-Mediated Insulin
Resistance Through Wingless Signaling
by Susumu Hirabayashi, Thomas J. Baranski, and Ross L. Cagan


Modeling Cancer with Flies and Fish
by Ross L. Cagan, Leonard I. Zon and Richard M. White
Building avatar armies with flies and fish
by Ellen P. Neff


Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
by Arvin C. Dar, Tirtha K. Das, Kevan M. Shokat, and Ross L. Cagan
Polypharmacology in Precision Oncology: Current Applications and Future Prospects
by Albert A. Antolina, Paul Workman, Jordi Mestres and Bissan Al-Lazikani


Targeting the cancer kinome through polypharmacology
by Zachary A. Knight, Henry Lin and Kevan M. Shokat
Development and clinical application of an integrative genomic approach to personalized cancer therapy
by Andrew V. Uzilov, Wei Ding, Marc Y. Fink, Yevgeniy Antipin, Andrew S. Brohl, Claire Davis, Chun Yee Lau, Chetanya Pandya, Hardik Shah, Yumi Kasai, James Powell, Mark Micchelli, Rafael Castellanos, Zhongyang Zhang, Michael Linderman, Yayoi Kinoshita, Micol Zweig, Katie Raustad, Kakit Cheung, Diane Castillo, Melissa Wooten, Imane Bourzgui, Leah C. Newman, Gintaras Deikus, Bino Mathew, Jun Zhu, Benjamin S. Glicksberg, Aye S. Moe, Jun Liao, Lisa Edelmann, Joel T. Dudley, Robert G. Maki, Andrew Kasarskis, Randall F. Holcombe, Milind Mahajan, Ke Hao, Boris Reva, Janina Longtine, Daniela Starcevic, Robert Sebra, Michael J. Donovan, Shuyu Li, Eric E. Schadt and Rong Chen


Minimal functional driver gene heterogeneity among untreated metastases
by Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Alexander Heyde, Marc A. Attiyeh, Zachary A. Kohutek, Collin J. Tokheim, Alexia Brown, Rayne M. DeBlasio, Juliana Niyazov, Amanda Zucker, Rachel Karchin, Kenneth W. KinzlerChristine A. Iacobuzio-Donahue, Bert Vogelstein and Martin A. Nowak
An analysis of genetic heterogeneity in untreated cancers
by Johannes G Reiter, Marina Baretti, Jeffrey M Gerold, Alvin P Makohon-Moore, Adil Daud, Christine A Iacobuzio-Donahue, Nilofer S Azad, Kenneth W Kinzler, Martin A Nowak and Bert Vogelstein

Ready to get started?
Contact us now and we’ll get you started. Alternatively, you can visit our other pages to learn more.