What we do

Mass in vivo analysis

What we do

Mass in vivo analysis

Personal Discovery ProcessTM
replicates a patient’s genetic profile and screens thousands of drug cocktails

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1  Patient’s entire exome analysed to capture tumour network

 

 

 

2  Mutations comprising patient’s tumour network engineered into fruit fly avatar

 

Fly
Fly

 

3  All FDA approved drugs screened – up to half a million avatars

 

 

4  Treatment recommendations report – generally for combination therapy

 

Fly

The Personal Discovery Process (PDP) provides individuals with treatment-driven research on an unprecedented scale. It is effectively a massive clinical trial for a single patient. We engineer the genetic complexity of each patient’s unique tumour network into an army of 500,000 fruit fly “avatars”. Using robotics, we evaluate up to 2,000 FDA approved drugs including non-cancer drugs, to identify drug combinations that are efficacious in the individual’s avatar population.

The Icahn School of Medicine at Mount Sinai developed the PDP methodology over years of clinical research. They found that real-world patient tumours are made resistant to single-drug treatments by mutations in several genes, including genes not previously associated with cancer. Such resistant tumours can however, be effectively addressed with novel combinations of FDA approved drugs. The most effective combinations almost always include non-cancer drugs. The Personal Discovery Process methods are licensed exclusively to My Personal Therapeutics (trading as Vivan Therapeutics).

Logo Perlara
Logo Genomics England
Logo Mount Sinai
Logo NIHR

 

Our Partners

 

Backed by

Logo Mount Sinai
Logo NIHR
Logo Perlara
Logo Genomics England

 

Media and Press

Logo Genome Web
Logo New Scientist
Logo Science Advances
Logo Forbes

Where to meet us next

A
Singapore Week of Innovation and Technology (SWITCH)

November 8-12. Click for more details

A
8th Annual BioCentury-BayHelix China Healthcare Summit

Presenter: Laura Towart, CEO Vivan Therapeutics

November 18-19. Click for more details

A
Advanced Therapies Live 2022

May 23-25 2022. Click for more details

Order now or contact us to learn more