Publications

The research powering the work we do.

Because every person, and every tumour, is different.

A genetic custom-made in vivo drug screening platform for colorectal cancer patients

by Cristina de Miguel, Andrea Chai, Annick Sawala, Laura Towart and Nahuel Vilegas

Mount Sinai

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

by Erdem Bangi, Celina Ang, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Hope Rainey, Aye S. Moe, Chun Yee Lau, Patricia Taik, Eric Wilck, Aarti Bhardwaj, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Eric E. Schadt, Marshall R. Posner and Ross L. Cagan

A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma

by Erdem Bangi, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Sindhura Gopinath, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Huan Wang, Jorge omez, John Mascarenhas, Aye S. Moe, Chun Yee Lau, Patricia Taik, Chetanya Pandya, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Celina Ang, Eric E. Schadt, Marshall R. Posner and Ross L. Cagan

Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function

by Santiago Nahuel Villegas, Dolors Ferres-Marco, María Domínguez

One hundred years of Drosophila cancer research: no longer in solitude

by Santiago Nahuel Villegas

Functional exploration of colorectal cancer genomes using Drosophila

by Erdem Bangi, Claudio Murgia, Alexander G.S. Teague, Owen J. Sansom and Ross L. Cagan

Transformed Drosophila Cells Evade Diet-Mediated Insulin
Resistance Through Wingless Signaling

by Susumu Hirabayashi, Thomas J. Baranski, and Ross L. Cagan

Modeling Cancer with Flies and Fish

by Ross L. Cagan, Leonard I. Zon and Richard M. White

Building avatar armies with flies and fish

by Ellen P. Neff

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

by Arvin C. Dar, Tirtha K. Das, Kevan M. Shokat, and Ross L. Cagan

Polypharmacology in Precision Oncology: Current Applications and Future Prospects

by Albert A. Antolina, Paul Workman, Jordi Mestres and Bissan Al-Lazikani

Targeting the cancer kinome through polypharmacology

by Zachary A. Knight, Henry Lin and Kevan M. Shokat

Development and clinical application of an integrative genomic approach to personalized cancer therapy

by Andrew V. Uzilov, Wei Ding, Marc Y. Fink, Yevgeniy Antipin, Andrew S. Brohl, Claire Davis, Chun Yee Lau, Chetanya Pandya, Hardik Shah, Yumi Kasai, James Powell, Mark Micchelli, Rafael Castellanos, Zhongyang Zhang, Michael Linderman, Yayoi Kinoshita, Micol Zweig, Katie Raustad, Kakit Cheung, Diane Castillo, Melissa Wooten, Imane Bourzgui, Leah C. Newman, Gintaras Deikus, Bino Mathew, Jun Zhu, Benjamin S. Glicksberg, Aye S. Moe, Jun Liao, Lisa Edelmann, Joel T. Dudley, Robert G. Maki, Andrew Kasarskis, Randall F. Holcombe, Milind Mahajan, Ke Hao, Boris Reva, Janina Longtine, Daniela Starcevic, Robert Sebra, Michael J. Donovan, Shuyu Li, Eric E. Schadt and Rong Chen

Minimal functional driver gene heterogeneity among untreated metastases

by Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Alexander Heyde, Marc A. Attiyeh, Zachary A. Kohutek, Collin J. Tokheim, Alexia Brown, Rayne M. DeBlasio, Juliana Niyazov, Amanda Zucker, Rachel Karchin, Kenneth W. KinzlerChristine A. Iacobuzio-Donahue, Bert Vogelstein and Martin A. Nowak

An analysis of genetic heterogeneity in untreated cancers

by Johannes G Reiter, Marina Baretti, Jeffrey M Gerold, Alvin P Makohon-Moore, Adil Daud, Christine A Iacobuzio-Donahue, Nilofer S Azad, Kenneth W Kinzler, Martin A Nowak and Bert Vogelstein

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